ChemInform Abstract: Rhodium(III)-Catalyzed Olefinic C-H Alkynylation of Enamides at Room Temperature

Rh(III)-catalyzed C–H olefinic alkynylation of enamides for the stereospecific construction of synthetically useful Z-type enynamides is reported. This protocol displays good functionality tolerance and operational simplicity thus providing an alternative synthetic opportunity for the ease of access to specific 1,3-enyne derivatives.