ChemInform Abstract: Phase Transfer Catalyzed Enantioselective Cyclopropanation of 4-Nitro-5-styrylisoxazoles

Authors :: Linda Piras
Francesco Fini
Claudia Del Fiandra
Maria Moccia
Mauro F. A. Adamo
Paolo Disetti
Source :: ChemInform. 43
Publication Year :: 2012
Publisher :: Wiley, 2012.
Abstract: The cyclopropanation of styryl isoxazoles (I) as cinnamate equivalents with bromomalonate (II) in the presence of a Cinchona alkaloid derived phase-transfer catalyst affords highly substituted cyclopropanes (III) in high yields, complete diastereo- and high enantioselectivity.

Subjects :: biology
Chemistry
Cyclopropanation
Phase (matter)
Organocatalysis
Nitro
Enantioselective synthesis
Cinchona
Organic chemistry
General Medicine
biology.organism_classification
Catalysis

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