Zentralerregende Wirkung eines neuen Piperidinderivates

A new piperidine derivative, the 2-diphenylmethylpiperidine, produces already in doses of 0.001 g/kg s.c. a strong increase of the spontaneous motility of various animals. On mice it has about the same potency as d-desoxy-ephedrine and is about 3 times more potent than amphetamin. It also acts markedly antagonistic on various narcotics but has practically no peripheral sympathomimetic effects.