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Preferences for first-line treatment of advanced urothelial carcinoma among US practicing oncologists and patients
- Source :
- Future Oncology. 19:369-383
- Publication Year :
- 2023
- Publisher :
- Future Medicine Ltd, 2023.
-
Abstract
- Aim: Investigate oncologist and patient preferences for the first-line treatment of advanced urothelial carcinoma. Materials & methods: A discrete-choice experiment was used to elicit treatment attribute preferences, including patient treatment experience (number and duration of treatments and grade 3/4 treatment-related adverse events), overall survival and treatment administration frequency. Results: The study included 151 eligible medical oncologists and 150 patients with urothelial carcinoma. Both physicians and patients appeared to prefer treatment attributes related to overall survival, treatment-related adverse events and the number and duration of the medications in a regimen over frequency of administration. Overall survival had the most influence in driving oncologists' treatment preferences, followed by the patient’s treatment experience. Patients found the treatment experience the most important attribute when considering options, followed by overall survival. Conclusion: Patient preferences were based on treatment experience, while oncologists preferred treatments that prolong overall survival. These results help to direct clinical conversations, treatment recommendations and clinical guideline development.
- Subjects :
- Cancer Research
Oncology
General Medicine
Subjects
Details
- ISSN :
- 17448301 and 14796694
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- Future Oncology
- Accession number :
- edsair.doi...........71c42b26aacddc3ab81459124c9d5fe2