Five New Cycloartane-Type Triterpenoid Saponins fromNervilia fordii

Five new cycloartane glycosides, nervisides D–H (1–5), were isolated from the AcOEt- and H2O-soluble portions of the 90% EtOH extract of the aerial part of the plant Nervilia fordii. The structures of the isolated glycosides were elucidated by extensive spectroscopic analysis including HR-ESI-MS and NMR data. The isolated nervisides D–H were evaluated for the cytotoxic activity in vitro against human-tumor cell lines (CNE, Hep-2 and HepG2) with the MTT method.