Back to Search
Start Over
Ratiometric fluorescent probe based on pyrrole-modified rhodamine 6G hydrazone for the imaging of Cu2+ in lysosomes
- Source :
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 212:121-127
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- A novel rhodamine-based Schiff base derivative was obtained via the simple condensation of substituted formyl-1H-pyrrole and rhodamine 6G hydrazone. Fluorescence resonance energy transfer enabled the subsequent use of the derivative as a naked-eye colorimetric and ratiometric fluorescent sensor for Cu2+ in semi-aqueous solution, and the existence of the morpholine group enabled the further application of the sensor in imaging Cu2+ in the lysosomes of HeLa cells.
- Subjects :
- chemistry.chemical_classification
Schiff base
Hydrazone
02 engineering and technology
010402 general chemistry
021001 nanoscience & nanotechnology
Photochemistry
01 natural sciences
Fluorescence
Atomic and Molecular Physics, and Optics
0104 chemical sciences
Analytical Chemistry
Rhodamine 6G
Rhodamine
chemistry.chemical_compound
Förster resonance energy transfer
chemistry
Morpholine
0210 nano-technology
Instrumentation
Spectroscopy
Derivative (chemistry)
Subjects
Details
- ISSN :
- 13861425
- Volume :
- 212
- Database :
- OpenAIRE
- Journal :
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
- Accession number :
- edsair.doi...........733b6c914858342925cc758167bbb0b7