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Synthesis, Characterization and Antitumor Activities of Cis-Ammine Gallic Acid(cyclohexylamine)Platinum(II)

Synthesis, Characterization and Antitumor Activities of Cis-Ammine Gallic Acid(cyclohexylamine)Platinum(II)

Authors :
Quan Jin
Li Min Zhou
Ze Bing Zhu
Yong Nian Li
Xue Jie Li
Jian He
Shao Ping Pu
Qing Kun Wang
Source :
Advanced Materials Research. :210-213
Publication Year :
2012
Publisher :
Trans Tech Publications, Ltd., 2012.

Abstract

In order to obtain a gallic acid platinum complex, the title compound was synthesed from cis-[Pt(Cyclohexylamine)]2I2 by the reaction with NH3, silver nitrate and gallic acid respectively. The complex structure and component were characterized by elemental analysis, ESI-MS, 1H-NMR and IR and the anticancer activity was measured by MTT method. The result showed that its structure was consistent with the title compound and had inhibiting effect on the growth of tumor cell lines in vitro.

Details

ISSN :
16628985
Database :
OpenAIRE
Journal :
Advanced Materials Research
Accession number :
edsair.doi...........736f871cc0b37cb54fe3c635507da2c0
Full Text :
https://doi.org/10.4028/www.scientific.net/amr.581-582.210