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Latex membranes with methylene blue dye for antimicrobial photodynamic therapy

Authors :
Josmary R. Silva
Paula C. S. Souto
João V.P. Valverde
Kevin F. dos Santos
Rita P. Ribeiro
Hérica Dias da Rocha
Marco A. C. de Faria
Nara C. de Souza
Marcos S. Sousa
Maria A. Oliveira de Sousa
Source :
Photochemical & Photobiological Sciences. 20:1027-1032
Publication Year :
2021
Publisher :
Springer Science and Business Media LLC, 2021.

Abstract

The search for new materials that can be applied in the treatment of injured human tissues has led to the development of new dressings. Membranes have potential as dressing materials because they can be fitted to and interact with the tissue surface. In this study, we analyze the morphological properties and wettability of latex membranes, along with the incorporation of the photosensitizer methylene blue, in the context of the utility of the membranes in curative applications involving photodynamic therapy (PDT). It was observed that deposition of the photosensitizer into latex membranes increased both the surface roughness and wettability. Antifungal testing indicated that antimicrobial PDT assisted by the latex membranes incorporating methylene blue effectively inactivated Candida albicans.

Details

ISSN :
14749092 and 1474905X
Volume :
20
Database :
OpenAIRE
Journal :
Photochemical & Photobiological Sciences
Accession number :
edsair.doi...........754c9e0c690bab88818de13aa72ae14f
Full Text :
https://doi.org/10.1007/s43630-021-00077-z