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A new sensitive gas-chromatographic method for the determination of fenfluramine in biological specimens

Authors :
Giorgio Belvedere
Gianni Tognoni
Paolo L. Morselli
Source :
European Journal of Clinical Pharmacology. 5:62-64
Publication Year :
1972
Publisher :
Springer Science and Business Media LLC, 1972.

Abstract

A new analytical procedure is described for the determination of fenfluramine and norfenfluramine in biological specimens. Fenfluramine and norfenfluramine are converted to the trichloroacetyl derivatives, separated on a 3% OV 17 — Chromosorb Q glass column and measured by ECD. The rapidity, sensitivity and specificity of the technique fulfil all the requirements for routine clinical use.

Details

ISSN :
14321041 and 00316970
Volume :
5
Database :
OpenAIRE
Journal :
European Journal of Clinical Pharmacology
Accession number :
edsair.doi...........76360689cebef370bab4807a630cd9a4
Full Text :
https://doi.org/10.1007/bf00560898