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EUTROC PiSARRO: A phase Ib study combining APR-246 with standard chemotherapy in platinum sensitive relapsed high grade serous ovarian carcinoma (HGSOC)
- Source :
- Journal of Clinical Oncology. 33:TPS5605-TPS5605
- Publication Year :
- 2015
- Publisher :
- American Society of Clinical Oncology (ASCO), 2015.
-
Abstract
- TPS5605 Background: p53 mutations are associated with increased chemoresistance. APR-246 is a small molecule that restores mutant p53 to wild type conformation and function (Lambert et al., Cancer ...
Details
- ISSN :
- 15277755 and 0732183X
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Oncology
- Accession number :
- edsair.doi...........76429a0ab7c45947fe9fc4c6cf07bfce