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Ferrocenyltriazoles from 3β,28-Diacylbetulin: Synthesis and Cytotoxic Activity
- Source :
- Russian Journal of Organic Chemistry. 55:1690-1697
- Publication Year :
- 2019
- Publisher :
- Pleiades Publishing Ltd, 2019.
-
Abstract
- The reaction of 30-bromo-3β,28-diacylbetulin with sodium azide afforded 30-azido-3β,28-diacyloxylup-20(29)-enes. The products were subjected to a CuI/TMEDA-catalyzed click reaction with ethynylferrocene to obtain the corresponding ferrocene-betulin conjugates with a 1,2,3-triazole linker.
Details
- ISSN :
- 16083393 and 10704280
- Volume :
- 55
- Database :
- OpenAIRE
- Journal :
- Russian Journal of Organic Chemistry
- Accession number :
- edsair.doi...........768baf47a89691182c05542031f22146
- Full Text :
- https://doi.org/10.1134/s1070428019110083