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Distinct patterns of clonal evolution in patients with concurrent myelo- and lymphoproliferative neoplasms

Authors :
John E. Dick
Mark D. Minden
Anne Tierens
Stephanie M. Dobson
Suzanne Kamel-Reid
Mahadeo A. Sukhai
Tracy Stockley
Vikas Gupta
James A. Kennedy
Jessie J. F. Medeiros
Andrea Arruda
Source :
Blood. 132:2201-2205
Publication Year :
2018
Publisher :
American Society of Hematology, 2018.

Abstract

TO THE EDITOR: BCR-ABL -negative myeloproliferative neoplasms (MPNs) are a group of clonal stem cell disorders characterized by the overproduction of mature myeloid cells. However, MPN patients also have a 2.8- to 3.4-fold increased risk of developing a lymphoproliferative disorder (LPD) compared

Details

ISSN :
15280020 and 00064971
Volume :
132
Database :
OpenAIRE
Journal :
Blood
Accession number :
edsair.doi...........76b6c67d36937da7f6a29823d1cc75ce
Full Text :
https://doi.org/10.1182/blood-2018-04-845065