ChemInform Abstract: Stereoselective Formation of Chiral trans-4-Hydroxy-5-substituted 2-pyrrolidinones: Syntheses of Streptopyrrolidine and 3-epi-Epohelmin A

Authors :: Guo-Qiang Lin
Chang-Mei Si
Zhen-Ting Du
Yi-Wen Liu
Zhuo-Ya Mao
Bang-Guo Wei
Source :: ChemInform. 47
Publication Year :: 2016
Publisher :: Wiley, 2016.
Abstract: A novel one-pot method for the diastereoselective synthesis of trans-4-hydroxy-5-substituted 2-pyrrolidinones via intramolecular cascade reaction of a series of Grignard reagents is presented.

Subjects :: Cascade reaction
Chemistry
Stereochemistry
Reagent
Intramolecular force
Stereoselectivity
General Medicine
Pyrrolidinones
Pyrrole derivatives

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