Synthesis of First Representatives of Isatin 1,2,3-Thiadiazolylcarbonylhydrazones

Authors :: Andrei V. Bogdanov
Vladimir F. Mironov
A. R. Gil’fanova
Yu. S. Shakhmina
A. D. Voloshina
T. A. Kalinina
Tatiana V. Glukhareva
Source :: Russian Journal of General Chemistry. 90:917-920
Publication Year :: 2020
Publisher :: Pleiades Publishing Ltd, 2020.
Abstract: The synthesis of new isatin derivatives containing the 1,2,3-thiadiazole ring in the hydrazone fragment was carried out. It was shown that the obtained compounds do not possess a hemolytic effect and do not exhibit cytotoxicity with respect to normal Chang liver human cell lines.

Subjects :: chemistry.chemical_classification
chemistry.chemical_compound
chemistry
Stereochemistry
Isatin
Hydrazone
General Chemistry
Human cell
Ring (chemistry)
Cytotoxicity

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