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Simple Preparation ofN-Benzyl-β-aminohydroxamic Acidsby 1,3-Dipolar Cycloaddition of Nitrones
- Source :
- Synthesis. 2003:1221-1224
- Publication Year :
- 2003
- Publisher :
- Georg Thieme Verlag KG, 2003.
-
Abstract
- β-Aminohydroxamic acids 6a-d are prepared in 4 steps and 30-45% overall yield from nitrones la-d by 1,3-dipolar cycloaddition with phenyl vinyl ether, N-benzylation, thermal rearrangement, and nucleophilic substitution ofthe formed phenyl ester with hydroxylamine.
Details
- ISSN :
- 1437210X and 00397881
- Volume :
- 2003
- Database :
- OpenAIRE
- Journal :
- Synthesis
- Accession number :
- edsair.doi...........784840e3d174c8ee306860919615af02
- Full Text :
- https://doi.org/10.1055/s-2003-39412