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Platinum based chemotherapy selects for PDGFRα dependent angiogenesis

Authors :
Alan W. Stitt
Laura A. Knight
Charlie Gourley
Richard D. Kennedy
Lara Dura Perez
Christopher Steele
Reinhold J. Medina
W. Glenn McCluggage
Richard H. Wilson
Aya El-Helali
Caroline O. Michie
Christina L. O'Neill
Stephen McQuaid
Andrena McCavigan
Nuala McCabe
Denis Paul Harkin
Jacqueline James
Source :
Journal of Clinical Oncology. 36:5578-5578
Publication Year :
2018
Publisher :
American Society of Clinical Oncology (ASCO), 2018.

Abstract

5578Background: Patients with High Grade Serous Ovarian Cancer (HGSOC) initially respond to SOC platinum based treatment but most will eventually relapse with platinum resistant disease. Angiogenes...

Details

ISSN :
15277755 and 0732183X
Volume :
36
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........7a1f2274d031ca8d238e731fab81e2bf