Back to Search
Start Over
Facile synthesis of γ-alkylidenebutenolides from Morita–Baylis–Hillman adducts
- Source :
- Tetrahedron Letters. 53:36-40
- Publication Year :
- 2012
- Publisher :
- Elsevier BV, 2012.
-
Abstract
- An expedient synthetic procedure of γ-alkylidenebutenolides was developed via a sequential indium-mediated Barbier-type reaction of Morita–Baylis–Hillman bromide with aldehyde, lactonization, and double-bond isomerization. Various γ-alkylidenebutenolides including bovolide and its derivatives were synthesized in good overall yields.
Details
- ISSN :
- 00404039
- Volume :
- 53
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters
- Accession number :
- edsair.doi...........7b50af6dccbf781fdbdf51ad260faf48
- Full Text :
- https://doi.org/10.1016/j.tetlet.2011.11.001