In physically active men, are the immune responses after performing a maximal aerobic capacity test dependent on chronological age and fitness level? A quasi-experimental, blinded study

Exercise immunology is the discipline that seeks to investigate the effects of exercise on the immune system of human beings. With advancing chronological age, the thymus (i.e., the organ responsible for T cell enhancement) involutes, which reduces the efficiency of the immune system, especially T cells. On the other hand, being physically conditioned provides long-term improvement of the immune system, regardless of age. However, it is known that strenuous exercise favors negative changes in the immune system. Thus, it is possible that changes in immunological factors after strenuous exercise depend on chronological age and level of physical conditioning.