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Synthesis of guanine 7-oxide, an antitumor antibiotic from species
- Source :
- Tetrahedron Letters. 28:1287-1290
- Publication Year :
- 1987
- Publisher :
- Elsevier BV, 1987.
-
Abstract
- The first synthesis of the antitumor antibiotic guanine 7-oxide (VI) has been achieved via a 4-step route starting from phenacyl bromide (I) and the nitropyrimidone III and proceeding through the intermediates IVe and Ve.
Details
- ISSN :
- 00404039
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters
- Accession number :
- edsair.doi...........7f0bfed262f6471ced3626ebece3027f
- Full Text :
- https://doi.org/10.1016/s0040-4039(00)95348-6