Rosmarinus officinalis directed palladium nanoparticle synthesis: Investigation of potential anti-bacterial, anti-fungal and Mizoroki-Heck catalytic activities

The present work was aimed to account a green and eco-friendly synthesis of palladium nanoparticles using Rosmarinus officinalis leaves extracts for the first time, therefore, that can be an acceptable replacement for chemical media to improve potential biological properties. The synthesized palladium nanoparticles were fully characterized using FT-IR, XRD, FESEM, TEM and UV/Vis spectroscopy techniques. Catalytic activity was investigated by Mizoroki-Heck reaction, and optimized based on solvent, temperature and time of the reaction, and the best results were found in water as a green media without any additional reagents. Biological activity of the synthesized nanoparticles were evaluated in terms of antibacterial and anti-fungal assessments against Staphylococcus aureus, Staphylococcus epidermidis, E. coli, and Micrococcus lutens bacteria’s and Candida parapsilolis, Candida albicans, Candida glabrata and Candida krusei fungus. Based on our knowledge, this is a comprehensive and first study on the catalytic and biological activity of palladium nanoparticles synthesizing from Rosmarinus officinalis, which presents great and significant results (in both catalytic and biological activities) based on a simple and green procedure.