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Myeloid sarcoma as a differential diagnosis of small bowel obstruction

Authors :
Nikos Emmanouilidis
Michael Winkler
Lothar Hambach
Mahmoud Abbas
B Ringe
Hans-Heinrich Kreipe
Bastian Kettler
Jürgen Klempnauer
Source :
Case Reports in Clinical Medicine. :173-176
Publication Year :
2013
Publisher :
Scientific Research Publishing, Inc., 2013.

Abstract

We are presenting the case of a 42-year-old male patient, who was hospitalized due to an acute small bowel obstruction caused by a tissue mass of the mesentery. The patient reported that he had a history of a testicular tumour. For therapy of intestinal obstruction as well as for diagnostic reasons we decided to perform an explorative laparotomy. On histopathological examination the immunohistological staining was positive for myeloperoxidase (MPO) and KP-1 (CD68). Staining was slightly positive for Bcl-2, CD117, CD34, but negative for CD3, CD4, CD5, CD8, CD20, CD30, CD79, Bcl-6 and S-100. This leads to the diagnosis of a myeloid sarcoma. After recovery from surgery and chemotherapy, allogenic bone marrow transplantation was performed. Most intestinal obstructions are caused by postoperative adhesions or hernias and only in rare cases caused by a myeloid sarcoma.

Details

ISSN :
23257083 and 23257075
Database :
OpenAIRE
Journal :
Case Reports in Clinical Medicine
Accession number :
edsair.doi...........7fa2a109fd972638c29f37ce3a4f8965
Full Text :
https://doi.org/10.4236/crcm.2013.22047