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High-Shear Rotor–Stator Wet Milling for Drug Substances: Expanding Capability with Improved Scalability

High-Shear Rotor–Stator Wet Milling for Drug Substances: Expanding Capability with Improved Scalability

Authors :
Aaron S. Cote
Luke Schenck
Allison Harter
Ivan C. Lee
Source :
Organic Process Research & Development. 17:1335-1344
Publication Year :
2013
Publisher :
American Chemical Society (ACS), 2013.

Abstract

Rotor–stator wet mills are commonly used in the pharmaceutical industry to reduce particle size and normalize API physical properties as a means to facilitate downstream drug product operations and...

Details

ISSN :
1520586X and 10836160
Volume :
17
Database :
OpenAIRE
Journal :
Organic Process Research & Development
Accession number :
edsair.doi...........7fe296f496ce005de673009b4ef6b28a
Full Text :
https://doi.org/10.1021/op4001143