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Effects of Res on proliferation and apoptosis of human cervical carcinoma cell lines C33A, SiHa and HeLa
- Source :
- Journal of Medical Colleges of PLA. 24:148-154
- Publication Year :
- 2009
- Publisher :
- Elsevier BV, 2009.
-
Abstract
- Objective To explore the effects of Res on the proliferation and apoptosis of human cervical cancer cell lines C33A, SiHa and HeLa. Methods Inhibition rates by different concentrations of Res were calculated using MTT method. Apoptosis rates and cell cycles were measured and examined by flow cytometry (FCM). Morphological configuration of apoptotic cells were observed under the fluorescence microscope. Results The growth of cancer cells was inhibited by Res of varied concentrations in a time- and dose-dependent manner (P Conclusion Res inhibits the growth of cervical cell lines C33A, SiHa and HeLa by inducing cell apoptosis in a time- and dose-dependent manner.
- Subjects :
- Oncology
medicine.medical_specialty
medicine.diagnostic_test
biology
Chemistry
General Medicine
Cell cycle
Resveratrol
biology.organism_classification
Flow cytometry
HeLa
chemistry.chemical_compound
Cell culture
Apoptosis
Internal medicine
Cancer cell
medicine
Cancer research
Fluorescence microscope
Subjects
Details
- ISSN :
- 10001948
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Journal of Medical Colleges of PLA
- Accession number :
- edsair.doi...........80a27053f8dcef5f9d38101c4c82076a