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A Mouse Model to Study Reparative Dentinogenesis
- Source :
- Methods in Molecular Biology ISBN: 9781493990115
- Publication Year :
- 2019
- Publisher :
- Springer New York, 2019.
-
Abstract
- Different animal models have been introduced recently to study the process of reparative dentinogenesis in response to injury-induced pulp exposure. Using a mouse model is advantageous over other animal models since mice can be genetically manipulated to examine specific cellular pathways and lineage trace the progeny of a single cell. However, enabling a standardized molar damage in mice is demanding due to the small size of the teeth compared to the available dental instruments. Here we describe a reproducible and reliable in vivo model that allows us to study dentinogenesis in the first maxillary mouse molar.
Details
- ISBN :
- 978-1-4939-9011-5
- ISBNs :
- 9781493990115
- Database :
- OpenAIRE
- Journal :
- Methods in Molecular Biology ISBN: 9781493990115
- Accession number :
- edsair.doi...........80a6c97e9a9725d741fda88aa461144c