First-in-man study of E-3810, a novel VEGFR and FGFR inhibitor, in patients with advanced solid tumors

Authors :: Angelo Delmonte
C. Dromain
Francesco Bertolini
Nathalie Lassau
E. Dall'O'
Massimo Zucchetti
Ratislav Bahleda
M. G. Camboni
Eric Angevin
Roberta Cereda
Françoise Farace
Jeannette Soria
Massimo Bellomi
Andreea Varga
S. Marsoni
F. de Braud
Cristina Noberasco
Source :: Journal of Clinical Oncology. 29:TPS149-TPS149
Publication Year :: 2011
Publisher :: American Society of Clinical Oncology (ASCO), 2011.
Abstract: TPS149 Background: Co-selective inhibition of VEGFRs and FGFR has the potential benefit of blocking the two most relevant players in tumor angiogenesis and simultaneously targeting proliferation in...

Subjects :: Tumor angiogenesis
Cancer Research
First-in-man study
biology
business.industry
Blocking (radio)
VEGF receptors
Pharmacology
Oncology
Fibroblast growth factor receptor
embryonic structures
Cancer research
biology.protein
Medicine
In patient
business
human activities

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