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RCM in indoles. A new entry to the mitosene skeleton

Authors :
Patxi Gonzalez‐Perez
Gema Domínguez
Javier Pérez-Castells
Leticia Perez‐Serrano
Luis Casarrubios
Source :
Tetrahedron Letters. 43:4765-4767
Publication Year :
2002
Publisher :
Elsevier BV, 2002.

Abstract

The RCM metathesis reaction catalyzed by Grubbs’ ruthenium catalyst is used with a series of 1,2-disubstituted indoles leading with excellent yields to tricyclic compounds. When applied to 1-allyl-2-vinylindoles this methodology allows a new entry to the mitosene skeleton.

Subjects

Subjects :
Ring-closing metathesis
Chemistry
Organic Chemistry
Drug Discovery
Salt metathesis reaction
chemistry.chemical_element
Organic chemistry
Ruthenium catalyst
Skeleton (category theory)
Biochemistry
Catalysis
Ruthenium

Details

ISSN :
00404039
Volume :
43
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........81554c9cf78a2708b12bafc9b8309913
Full Text :
https://doi.org/10.1016/s0040-4039(02)00909-7
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