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Neuroprotective effect of aloe emodin against Huntington's disease-like symptoms in R6/1 transgenic mice
- Source :
- Food & Function.
- Publication Year :
- 2023
- Publisher :
- Royal Society of Chemistry (RSC), 2023.
-
Abstract
- Aloe emodin attenuated motor and cognitive dysfunction in HD model mice. Aloe emodin decreased the level of the mutant huntingtin protein and inhibited CaMKII/Smad and TGF-β1/Smad signaling.
- Subjects :
- General Medicine
Food Science
Subjects
Details
- ISSN :
- 2042650X and 20426496
- Database :
- OpenAIRE
- Journal :
- Food & Function
- Accession number :
- edsair.doi...........81c3055d73ae3ec662e6536b1c31941f