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A Short Synthesis of Clionamine D
- Source :
- Chinese Journal of Chemistry. 33:1235-1238
- Publication Year :
- 2015
- Publisher :
- Wiley, 2015.
-
Abstract
- Herein we describe a scalable four-step preparation of α-methylene-γ-lactone 3 from steroidal sapogenin. This method allowed a facile synthesis of clionamine D, a natural aminosteroid with potent autophagy bioactivity and unprecedented chemical structure.
Details
- ISSN :
- 1001604X
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Chinese Journal of Chemistry
- Accession number :
- edsair.doi...........82d8c76ee8573ba43df52bae9f5efa0b
- Full Text :
- https://doi.org/10.1002/cjoc.201500652