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Room temperature MgI2-catalyzed Friedel–Crafts reaction between electron-rich (het)arenes and ethyl glyoxylate

Authors :
Irina P. Beletskaya
Boris A. Lozhkin
Maksim V. Anokhin
Mikhail Feofanov
A. D. Averin
Source :
Mendeleev Communications. 28:429-430
Publication Year :
2018
Publisher :
Elsevier BV, 2018.

Abstract

Magnesium iodide-catalyzed addition of electron-rich (het)arenes to ethyl glyoxylate proceeds at room temperature with high chemoselectivity to afford ethyl 2-(het)aryl- 2-hydroxyacetates in yields up to 95%.

Details

ISSN :
09599436
Volume :
28
Database :
OpenAIRE
Journal :
Mendeleev Communications
Accession number :
edsair.doi...........83df17d9dc24da6dca33930d1fa7be2d
Full Text :
https://doi.org/10.1016/j.mencom.2018.07.030