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A Phase 2a, Double-Blind, Placebo-controlled Randomized Trial of Inhaled TLR9 Agonist AZD1419 in Asthma
A Phase 2a, Double-Blind, Placebo-controlled Randomized Trial of Inhaled TLR9 Agonist AZD1419 in Asthma
- Source :
- American Journal of Respiratory and Critical Care Medicine. 203:296-306
- Publication Year :
- 2021
- Publisher :
- American Thoracic Society, 2021.
-
Abstract
- Rationale: To examine the potential of TLR9 (Toll-like receptor 9) activation to modulate the type 2 immune response in asthma.Objectives: To evaluate efficacy and safety of AZD1419, an inhaled TLR...
- Subjects :
- Pulmonary and Respiratory Medicine
Agonist
business.industry
medicine.drug_class
TLR9
chemical and pharmacologic phenomena
Pharmacology
Critical Care and Intensive Care Medicine
medicine.disease
Placebo
Type 2 immune response
law.invention
Double blind
03 medical and health sciences
0302 clinical medicine
030228 respiratory system
Randomized controlled trial
immune system diseases
law
Medicine
030212 general & internal medicine
business
Receptor
Asthma
Subjects
Details
- ISSN :
- 15354970 and 1073449X
- Volume :
- 203
- Database :
- OpenAIRE
- Journal :
- American Journal of Respiratory and Critical Care Medicine
- Accession number :
- edsair.doi...........84412c619305c6b024e21c1e75b3f234
- Full Text :
- https://doi.org/10.1164/rccm.202001-0133oc