A new reagent for the cleavage of fully protected peptides synthesised on 2-chlorotrityl chloride resin

Authors :: Ralf Bollhagen
Ernst Grell
Monika Schmiedberger
Kleomenis Barlos
Source :: Journal of the Chemical Society, Chemical Communications. :2559
Publication Year :: 1994
Publisher :: Royal Society of Chemistry (RSC), 1994.
Abstract: A mixture of hexafluoroisopropanol–dichloromethane (1:4 v/v) acts as a fast, effective and convenient reagent for cleaving protected peptide fragments with a minimal amount of racemization from 2-chlorotrityl chloride resin.

Subjects :: chemistry.chemical_classification
Chemistry
Reagent
medicine
2-chlorotrityl chloride
Molecular Medicine
Organic chemistry
Peptide
Cleavage (embryo)
Chloride
Racemization
medicine.drug

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