tert-Butyl nitrite mediated azo coupling between anilines and imidazoheterocycles

A tBuONO mediated practical and efficient method for the synthesis of azo imidazoheterocycles with broad functionalities has been achieved by the reaction between imidazoheterocycles and anilines at room temperature in goods yields. Azo indolizines were also prepared by employing this methodology. Mild reaction conditions, tolerance of wide functionalities, operational simplicity and easy purification of the products are the notable advantages of the current protocol.