Two decades of oncology randomized controlled trials: Factors associated with CONSORT clinical trial reporting checklist compliance

6126 Background: The Consolidated Standards for Reporting Trials (CONSORT) checklist has been formulated to improve the reporting of randomized controlled trials (RCTs). The purpose of this investigation is to determine predictors of CONSORT checklist compliance in the oncology literature over the past two decades. Methods: Eight-hundred and fifty parallel two-arm RCTs assessing oncological interventions in adult breast, prostate, colorectal, and lung cancer between 1992-2010 were identified by a systematic search of the medical literature. Exclusion criteria included investigations reporting interim/secondary/long-term update analyses, pilot/phase 2 studies and studies not employing a parallel design. After full article review, 408 articles were eligible for inclusion into the CONSORT audit database. RCT descriptive variables including number of authors/study patients, 2009 journal impact factor/journal classification, type of cancer and therapeutic intervention, publication year, primary study country, ...