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Assessment of Peste des petits ruminants antibodies in vaccinated pregnant Kano brown does from Nigeria and subsequent maternal immunity in their kids

Authors :
Haruna Makanjuola Kazeem
Timothy Yusufu Woma
Talatu Patience Markus
Olushola Samuel Olaolu
Jibril Adamu
Source :
Small Ruminant Research. 174:53-56
Publication Year :
2019
Publisher :
Elsevier BV, 2019.

Abstract

Peste des petits ruminants (PPR) is an endemic disease of small ruminants in Nigeria and routine vaccination is the mainstay for its prevention and control. This study was aimed to assess PPR antibodies in vaccinated pregnant does and subsequent maternal immunity in their kids post parturition (PP). Twelve apparently healthy pregnant Kano brown does were used for this study. Pregnancy (third trimester) was confirmed by ultrasonography. Does were vaccinated using Nigerian 75/1 PPR strain vaccine produced by the National Veterinary Research Institute (NVRI) Vom, Nigeria. Blood was collected from does and sera harvested pre-vaccination (PrV), one week post vaccination (PV) and at two weeks interval for up to 12 weeks PP. Sera were collected from kids at two weeks of age and at two weeks interval for up to 12 weeks PP. Sera were tested for PPR antibodies using competitive enzyme linked immunosorbent assay (c-ELISA). Results showed that 100% of vaccinated does had and maintained protective PPR antibodies PV. There was significant difference (P

Details

ISSN :
09214488
Volume :
174
Database :
OpenAIRE
Journal :
Small Ruminant Research
Accession number :
edsair.doi...........86ea5cf8f91516d9f939123baa407d30
Full Text :
https://doi.org/10.1016/j.smallrumres.2019.03.009