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Development and Scale-Up of an Optimized Route to the ALK Inhibitor CEP-28122
- Source :
- Organic Process Research & Development. 16:148-155
- Publication Year :
- 2012
- Publisher :
- American Chemical Society (ACS), 2012.
-
Abstract
- Evolution of the process strategies to prepare CEP-28122, an anaplastic lymphoma kinase (ALK) inhibitor, is presented. The initial medicinal chemistry route, used for the preparation of key supplie...
Details
- ISSN :
- 1520586X and 10836160
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- Organic Process Research & Development
- Accession number :
- edsair.doi...........87652bb6c8d2133a00f6705e1d407d35
- Full Text :
- https://doi.org/10.1021/op200313v