A Visible Light Driven Direct synthesis of Industrially Relevant Glutaric Acid Diesters from Aldehydes

A direct access to a-substituted glutaric diesters from acrylates and aldehydes by exploring the HAT property of Eosin Y followed by consecutive Giese type addition to construct substituted glutaric diesters. The practicality of the protocol has been demonstrated with a wide range of substrate scope. We have also successfully performed the transformation under direct exposure of natural sunlight as a light source to achieve the sustainability. As an application of this protocol, the biologically potent and industrially relevant substituted 4,5-dihydro-2H pyridazinones have also been directly synthesized from substituted glutaric diesters. A detailed and systematic control experiments have been carried out to investigate the plausible mechanistic pathway.