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Permissive, nonpermissive HLA-DPB1 epitope disparities and the specificity of T cells infiltrating the skin during acute graft-versus-host disease

Authors :
Noel Milpied
Joëlle Gaschet
Henri Vié
Source :
Blood. 117:5779-5781
Publication Year :
2011
Publisher :
American Society of Hematology, 2011.

Abstract

To the editor: Human leukocyte antigen (HLA)–DPB1 functions as a classic transplantation antigen.[1][1] In the context of hematopoietic stem cell transplantation (HSCT), when donor T cells recognize host HLA-DP, they can induce a graft-versus-host disease (GVHD) and/or a graft-versus-leukemia (

Details

ISSN :
15280020 and 00064971
Volume :
117
Database :
OpenAIRE
Journal :
Blood
Accession number :
edsair.doi...........88f4f9cecb7806586f335f8a4e51640f
Full Text :
https://doi.org/10.1182/blood-2011-02-338533