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Highly regioselective palladium-catalyzed condensation of terminal acetylenes with 2,5-diiodobenzoic acid

Authors :
Charles Mioskowski
Fabrice Balavoine
David Madec
Source :
Tetrahedron Letters. 40:8351-8354
Publication Year :
1999
Publisher :
Elsevier BV, 1999.

Abstract

Palladium-catalyzed coupling reactions between terminal alkynes and 2,5-diiodobenzoic acid have been shown to be highly regioselective, giving a rapid and efficient route for the synthesis of disymmetric 2,5-bis ethynyl benzoic acid derivatives.

Details

ISSN :
00404039
Volume :
40
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........8ad58c5f9663a249868a94f6bd4c04c2