Role of the Vagal Nerve in the Development of Gastric Mucosal Injury and its Prevention by Atropine, Cimetidine, β-Carotene and Prostacyclin in Rats

Peptic ulceration including acute erosions is a multifactorial disease involving well-known factors such as trauma, stress, sepsis, hemorrhagic shock, burns, pulmonary and liver diseases1–9 and drugs such as reserpine10, epinephrine11–13, nonsteroidal antiinflammatory drugs7, steroids and other chemicals14.