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Agar-based phantoms for skin diagnostic imaging

Authors :
Janis Spigulis
Anna Maslobojeva
Laura Dambite
Ilona Kuzmina
Uldis Rubins
Vanesa Lukinsone
Ilze Osina
Source :
Tissue Optics and Photonics.
Publication Year :
2020
Publisher :
SPIE, 2020.

Abstract

Agar-based skin phantoms with different thicknesses and hemoglobin concentration were evaluated for diagnostics of skin lesions by RGB imaging. Scattering properties of the phantoms were simulated using intralipid, absorption properties – using lyophilized powder of human hemoglobin. RGB images of phantoms were captured by self-developed laboratory made devices. The algorithm for calculation of chromophore concentrations are based on Beer-Lambert law and includes the photon path length evaluated from the measured photon-time-of-flight signals. Optical properties and chromophore concentration maps of phantoms obtained from RGB images were analyzed. The influence of chromophore concentration on scattering and absorption, photon path length and chromophore maps are discussed.

Details

Database :
OpenAIRE
Journal :
Tissue Optics and Photonics
Accession number :
edsair.doi...........8d351f49291c1701072edad347f730a9
Full Text :
https://doi.org/10.1117/12.2555674