Cordyceps sinensis-mediated biotransformation of notoginsenoside R1 into 25-OH-20(S/R)-R2 with elevated cardioprotective effect against DOX-induced cell injury

Authors :: Jishuang Liu
Yu Xin
Zhidong Qiu
Qi Zhang
Tianzhu He
Ye Qiu
Weinan Wang
Source :: RSC Advances. 12:12938-12946
Publication Year :: 2022
Publisher :: Royal Society of Chemistry (RSC), 2022.
Abstract: The biocatalytic system in this paper preferably yielded 25-OH notoginsenoside R2 from R1 in a regioselective manner. Such a process significantly elevated the effects of these 25-OH derivatives against DOX-induced cardiomyocyte injury.

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