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Adaptogenic and Neuroprotective Properties of Lithium Ascorbate

Authors :
K. S. Ostrenko
O. A. Gromova
V. V. Rastashansky
Source :
Journal Biomed. 18:122-127
Publication Year :
2022
Publisher :
Scientific Center for Biomedical Technologies of the Federal Medical-Biological Agency, 2022.

Abstract

In this work, we study the neuroprotective properties of lithium ascorbate in in vivo and in vitro stress models. Neurocytological and behavioral studies were carried out on models of stress in both a culture of nerve cells and experimental animals. The studied drug showed a significant neuroprotective effect of lithium ascorbate in neuronal cultures exposed to glutamate toxicity and an adaptogenic effect in stress models in rats. The results suggest that lithium ascorbate possess a high neuroprotective potential in stress models in vivo and in vitro.

Subjects

Subjects :
General Medicine

Details

ISSN :
27130428 and 20745982
Volume :
18
Database :
OpenAIRE
Journal :
Journal Biomed
Accession number :
edsair.doi...........8ddf6a59884aa54323130c4cd126667a
Full Text :
https://doi.org/10.33647/2074-5982-18-3-122-127