Synthesis of Novel Modified Guanidines: Reaction of Dicyandiamide with Amino Acids, Amides, and Amines in Aqueous Medium

Reaction of dicyandiamide with series of amino acids afforded guanidinyl pyrazolones , respectively. Although reaction of dicyandiamide with urea, acetamide, bezamide, allantion, p-aminobenzoic acid, sulphanilic acid, and adenine gave biguanides , respectively. All compounds have been characterized on the basis of IR and 1H-NMR.