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Pulmonale Hypertonie
- Source :
- Der Anaesthesist. 65:635-652
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- Pulmonary hypertension (PH) comprises a group of pulmonary vascular diseases that are characterized by progressive exertional dyspnea and right heart insufficiency ultimately resulting in right heart decompensation. The classification is into five clinical subgroups that form the absolutely essential basis for decisions on the indications for different pharmacological and non-pharmacological forms of treatment. The guidelines were updated in 2015 and in addition to the hitherto existing pharmacological treatment options of phosphodiesterase type 5 inhibitors, endothelin receptor antagonists and prostacyclins, the soluble guanylate cyclase stimulator riociguat has now been incorporated for treatment of certain forms of PH. This article provides an overview of the new treatment recommendations in the current guidelines, e. g. for PH patients who are in intensive care units due to surgical interventions or progressive right heart insufficiency.
- Subjects :
- medicine.medical_specialty
business.industry
General Medicine
030204 cardiovascular system & hematology
Soluble Guanylate Cyclase Stimulator
medicine.disease
Riociguat
Pulmonary hypertension
03 medical and health sciences
0302 clinical medicine
Anesthesiology and Pain Medicine
Intensive care
Internal medicine
Right heart
Cardiology
Medicine
Decompensation
030212 general & internal medicine
business
Endothelin receptor
Soluble guanylyl cyclase
medicine.drug
Subjects
Details
- ISSN :
- 1432055X and 00032417
- Volume :
- 65
- Database :
- OpenAIRE
- Journal :
- Der Anaesthesist
- Accession number :
- edsair.doi...........8f8e30af3c6e1088e4444e2107272844
- Full Text :
- https://doi.org/10.1007/s00101-016-0207-y