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Update on Bicuspid Aortic Valve Syndrome: Patient Selection and Therapies in 2020
- Source :
- Current Treatment Options in Cardiovascular Medicine. 22
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- This article highlights our current understanding of bicuspid aortic valve (BAV) syndrome and how genetics, pathology, imaging features, and clinical symptoms direct the clinical management, surveillance, and intervention of those with BAV. While randomized data and guidelines are lacking, transcatheter therapies are routinely used for BAV stenosis in medical centers throughout the world. Guidelines suggest that younger patients age less than 50 years undergo surgical aortic valve replacement (AVR) with a mechanical valve and the elderly > 70 years of age receive a bioprosthetic valve. For the age group 50–70 years, either option should be considered. Decision on type of intervention depends on specific features such as presence of stenosis or regurgitation, if there is any associated aortopathy, comorbid illnesses, contraindications, and patient preference. We have learned that the decision to intervene and mode of intervention is best achieved by a multidisciplinary valve team. Despite improvement in our understanding of BAV and the advancement of novel therapies particularly for BAV stenosis, much is still to be learned about the optimal treatment of BAV disease in the current era.
- Subjects :
- medicine.medical_specialty
business.industry
Disease
Regurgitation (circulation)
030204 cardiovascular system & hematology
medicine.disease
Syndrome patient
Bioprosthetic valve
03 medical and health sciences
Stenosis
0302 clinical medicine
Bicuspid aortic valve
Aortic valve replacement
Intervention (counseling)
Medicine
030212 general & internal medicine
Cardiology and Cardiovascular Medicine
business
Intensive care medicine
Subjects
Details
- ISSN :
- 15343189 and 10928464
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Current Treatment Options in Cardiovascular Medicine
- Accession number :
- edsair.doi...........90b14d19521b43496b66a3f01fce105e