An in vitro haemolysis test as an alternative to the draize test for ocular irritation

Authors :: P. R. Sibley
C. M. Andrews
B. K. Singleton
S. E. Libretto
C. V. J. Mifsud
Source :: Comparative Haematology International. 4:49-54
Publication Year :: 1994
Publisher :: Springer Science and Business Media LLC, 1994.
Abstract: A haemolysis test has been evaluated as an alternative to the Draize eye test (Draize et al. 1944) for ocular irritancy. Haemolysis was seen with corrosive/ severe and severe/moderate eye irritants but was negligible with non-irritant substances.

Subjects :: medicine.medical_specialty
Pathology
genetic structures
business.industry
Ocular irritation
macromolecular substances
Hematology
Haemolysis
eye diseases
In vitro
Pathology and Forensic Medicine
Test (assessment)
nervous system
Ophthalmology
Medicine
Draize test
sense organs
Anatomy
business

Tools