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Copper-Catalyzed N-Arylation of Amides and Azoles Using Phosphine-Free Hydrazone Ligands
- Source :
- Synlett. 2008:614-620
- Publication Year :
- 2008
- Publisher :
- Georg Thieme Verlag KG, 2008.
-
Abstract
- Phosphine-free hydrazone such as 1c was found to be an efficient ligand for the copper-catalyzed Goldberg-type N-arylation of amides and Ullmann-type N-arylation of azoles with aryl halides under mild conditions. A variety of N-arylamides and N-arylazoles were synthesized in good to high yields.
Details
- ISSN :
- 14372096 and 09365214
- Volume :
- 2008
- Database :
- OpenAIRE
- Journal :
- Synlett
- Accession number :
- edsair.doi...........925918c1889bf9acd9f674d0749d7f91