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Effect of Weikang Capsule (胃康胶囊) on Aspirin-Related Gastric and Small Intestinal Mucosal Injury
- Source :
- Chinese Journal of Integrative Medicine. 27:621-625
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- To investigate the effects of Weikang Capsule (胃康胶囊, WKC) on aspirin-related gastric and small intestinal mucosal injury by magnetically controlled capsule endoscopy (MCCE). Patients taking enteric-coated aspirin aged 40–75 years were enrolled in Beijing Anzhen Hospital, Capital Medical University from January 2019 to December 2019. The patients continued taking aspirin Tablet (100 mg per day) and underwent MCCE before and after 1-month combined treatment with WKC (0.9 g per time orally, 3 times per day). The gastrointestinal symptom score, gastric Lanza score, the duodenal, jejunal and ileal mucosal injury scores were used to evaluate the gastrointestinal injury before and after treatment. Adverse events including nausea, vomiting, abdominal pain, abdominal distension, abdominal discomfort, dizziness, or headache during MCCE and combined treatment were observed and recorded. Twenty-two patients (male/female, 13/9) taking enteric-coated aspirin aged 59.5 ± 11.3 years with a duration of aspirin use of 28.0 (1.0, 48.0) months were recruited. Compared with pre-treatment, the gastrointestinal symptom rating scale scores, gastric Lanza scores, and duodenal mucosal injury scores were significantly reduced after 1-month WKC treatment (P
- Subjects :
- medicine.medical_specialty
Abdominal pain
Nausea
0211 other engineering and technologies
02 engineering and technology
030226 pharmacology & pharmacy
Gastroenterology
law.invention
03 medical and health sciences
0302 clinical medicine
Capsule endoscopy
law
Internal medicine
021105 building & construction
medicine
Pharmacology (medical)
Adverse effect
Aspirin
business.industry
General Medicine
Abdominal distension
Clinical trial
Complementary and alternative medicine
Vomiting
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 19930402 and 16720415
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Chinese Journal of Integrative Medicine
- Accession number :
- edsair.doi...........9277391bc5b924c524314258cd4ff891