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Demystifying the prothrombotic role of NETs
- Source :
- Blood. 129:925-926
- Publication Year :
- 2017
- Publisher :
- American Society of Hematology, 2017.
-
Abstract
- In this issue of Blood, Noubouossie and colleagues report surprising findings on the role of neutrophil-derived nuclear material in blood coagulation. The authors provide evidence that, in contrast to DNA and histone proteins, neutrophil extracellular traps (NETs) do not contribute directly to coagulation of human plasma. These findings implicate differential functions of nuclear material in thrombosis and are of importance for the development of antithrombotic therapies targeting NETs.(1)
- Subjects :
- 0301 basic medicine
biology
business.industry
Immunology
Cell Biology
Hematology
Neutrophil extracellular traps
030204 cardiovascular system & hematology
medicine.disease
Bioinformatics
Biochemistry
Thrombosis
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Histone
Coagulation
Antithrombotic
biology.protein
medicine
Thromboplastin
Platelet
business
Fibrinolytic agent
Subjects
Details
- ISSN :
- 15280020 and 00064971
- Volume :
- 129
- Database :
- OpenAIRE
- Journal :
- Blood
- Accession number :
- edsair.doi...........92f80ce7b115a00e1d800beb00d285e3