Thiol and Thioacetate Derivatives of Δ-Cadinene

Photochemical thioacetylation of (s−)- i -cadinene 1 afforded 5-acetylthio-cadinene 1a which was further reduced into 5-mercapto-cadinene 1b in good yield (80%). Thioepoxydation of trans -1,10-cadinene oxide 1c , prepared from m -CPBA oxidation of 1 , was also investigated. Structural determination of these derivatives was achieved by one- and two dimensional NMR spectroscopy.